If it does and the Game Genie model you're using lacks those connections, I assure you you'll have problems even if initial appearances suggest that it does work correctly. Additional Resources: The FC Twin Wikipedia Entry. That’s right, with the new FC Twin, you can play both NES and Super Nintendo games on the same machine. However, since I don't own either cartridge, I couldn't tell you if it has those extra pins to each side. This past November, a new NES clone upped the offerings by adding SNES support in tandem with NES capabilities. If so, it could appear to be functioning correctly until you reach a point in the game where that chip is utilized, where problems would be encountered if it utilizes those extra pins to each side of the primary cartridge board and the Game Genie lacks the connections to pass those through to the console.
Wikipedia's description states it was 'known for its role in mapping and transforming wireframes in the final scenes of Capcom's second and third Mega Man X series games', suggesting that it isn't in constant use just like the Super FX chip isn't in constant use in Yoshi's Island. Purchased a cheap 72 pin connector and used a non-working Famicom to NES connector for the pins. The genie grips my adapter tighter than the adapter grips the NES-101, so pulling it out wont leave the adapter. I'm unsure, I wasn't a big fan of that series and didn't play the 2nd and 3rd titles until the Mega Man X collection hit the GameCube. For those unaware, the game genie board is thicker and wont easily fit into the top loader like the front loader.